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Concerned about affording your Synthroid medication? RxSaver can help you save on prescription costs. Levothyroxine (Levoxyl, Synthroid, Tirosint) is a medication that's commonly prescribed for hypothyroidism (an underactive thyroid). Knowing how much levothyroxine costs is important, since you'll likely take it long term and want to plan for ongoing medication expenses. How much you pay for levothyroxine may depend on your dose, pharmacy, and whether you take generic levothyroxine or a … Synthroid prices and discounts | AARP Prescription Discounts If you have an allergy to levothyroxine or any other part of this drug. If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have any of these health problems: Overactive thyroid gland or weak adrenal gland. 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