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Brief Description of Sustiva Sustiva is a prescription medication that belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs). The active ingredient in Sustiva is efavirenz. It is primarily used in the treatment of HIV-1 infection in combination with other antiretroviral medications. Buy Sustiva online. Learn about Efavirenz, dosage, benefits, directions for use, precautions, and other essential product information. Get your Sustiva (Efavirenz) for only $70.00 per month through our patient assistance program. Enroll today and get pre-qualified. Sustiva Prices, Coupons, Copay Cards & Patient Assistance Prices Coupons Patient assistance Sustiva (efavirenz) is a member of the NNRTIs drug class and is commonly used for HIV-1 Infection, Nonoccupational Exposure, and Occupational Exposure. The cost for Sustiva 600 mg oral tablet is around $1,042 for a supply of 30 tablets, depending on the pharmacy you visit. 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